2. Signaling Pathways
  3. Metabolic Enzyme/Protease
    Neuronal Signaling
  4. Adenosine Kinase
  5. Adenosine Kinase Inhibitor

Adenosine Kinase Inhibitor

Adenosine Kinase Inhibitors (9):

Cat. No. Product Name Effect Purity
  • HY-15424
    5-Iodotubercidin
    		Inhibitor 99.64%
    5-Iodotubercidin (NSC 113939), an ATP mimetic, is a potent adenosine kinase inhibitor with an IC50 of 26 nM. 5-Iodotubercidin (NSC 113939) initiates glycogen synthesis in isolated hepatocytes by causing inactivation of phosphorylase and activation of glycogen synthase. 5-Iodotubercidin (NSC 113939) also inhibits CK1, insulin receptor tyrosine kinase, phosphorylase kinase, PKA, CK2, PKC and Haspin.
  • HY-103161
    ABT-702 dihydrochloride
    		Inhibitor 99.64%
    ABT-702 dihydrochloride is a potent adenosine kinase (AK) inhibitor (IC50=1.7 nM).
  • HY-148327
    AK-IN-1
    		Inhibitor 99.95%
    AK-IN-1 (compound 4072-2732) is an adenosine kinase (AK) inhibitor that is competitive for adenosine (Ado) but not for ATP. AK-IN-1 inhibits 86%, 87% and 89% of AK activity at concentrations of 2, 4 and 10 µM, respectively. AK-IN-1 has good potential for research in many disease areas, including ischaemia, inflammation and seizures.
  • HY-164887
    Adenosine Kinase siRNA-3
    		Inhibitor
    Adenosine Kinase siRNA-3 is a small interfering RNA (siRNA) targeting Adenosine Kinase that has a knockdown effect on Adenosine Kinase.
  • HY-164886
    Adenosine Kinase siRNA-2
    		Inhibitor
    Adenosine Kinase siRNA-2 is a small interfering RNA that targets adenosine kinase messenger RNA.
  • HY-116005
    A-286501
    		Inhibitor
    A-286501 is an orally active and potent carbocyclic nucleoside adenosine kinase inhibitor with an IC50 value of 0.47 nM, which shows analgesic and anti-inflammatory effects. A-286501 reduces nociception in animal models of acute (thermal), inflammatory (formalin and carrageenan) and neuropathic (L5/L6 nerve ligation and streptozotocin-induced diabetic) pain. A-286501 also reduces Carrageenan (HY-125474)-induced paw edema and myeloperoxidase activity in the injured paw. A-286501 is promising for research of analgesic and anti-inflammatory agents.
  • HY-164885
    Adenosine Kinase siRNA-1
    		Inhibitor 98.34%
    Adenosine Kinase siRNA-1 is a small interfering RNA (siRNA) targeting Adenosine Kinase that has a knockdown effect on Adenosine Kinase.
  • HY-19259
    GP3269
    		Inhibitor
    GP3269 is a potent, selective, and orally active inhibitor of human adenosine kinase (AK) with an IC50 of 11 nM. GP3269 exhibits anticonvulsant activity in rats.
  • HY-112482A
    ABT-702 hydrochloride
    		Inhibitor
    ABT-702 hydrochloride is a potent inhibitor of adenosine kinase with an IC50 of 1.7 nM.